Cezard A, Fouquenet D, Vasseur V, Jeannot K, Launay F, Si-Tahar M, Hervé V. Poly-L-Lysine to Fight Antibiotic Resistances of Pseudomonas aeruginosa. Int J Mol Sci. 2023 Feb 2;24(3):2851. doi: 10.3390/ijms24032851. PMID: 36769174; PMCID: PMC9917869.

Richter, F., Paget, C., & Apetoh, L. (2023). STING-driven activation of T cells : Relevance for the adoptive cell therapy of cancer. Cell Stress, 7(11), 95‑104. https://doi.org/10.15698/cst2023.11.291

Giret, C., Dos Santos, Y., Blasco, H., Paget, C., Gonzalez, L., Tressel, N., Dieu, M., Bigot, A., Gissot, V., Audemard-Verger, A., & Maillot, F. (2023). No evidence for systemic low-grade inflammation in adult patients with early-treated phenylketonuria : The INGRAPH study. JIMD Reports, 64(6), 446‑452. https://doi.org/10.1002/jmd2.12366

Pitiot A, Ferreira M, Parent C, Boisseau C, Cortes M, Bouvart L, Paget C, Heuzé-Vourc’h N, Sécher T. Mucosal administration of anti-bacterial antibodies provide long-term cross-protection against Pseudomonas aeruginosa respiratory infection. Mucosal Immunol. 2023 Mar 28:S1933-0219(23)00021-1. doi: 10.1016/j.mucimm.2023.03.005.

Alarcan, H., Berthet, M., Suire, L., Colas, C., Gonzalez, L., Paget, C., Benz-de Bretagne, I., Piver, E., Vourc’h, P., Andres, C., Corcia, P., & Blasco, H. (2022). Inflammatory mediators, lipoproteins and apolipoproteins in early diagnosis of amyotrophic lateral sclerosis. SLAS Technology, 27(5), 327‑334. https://doi.org/10.1016/j.slast.2022.07.003

Santoni, K., Pericat, D., Gorse, L., Buyck, J., Pinilla, M., Prouvensier, L., Bagayoko, S., Hessel, A., Leon-Icaza, S. A., Bellard, E., Mazères, S., Doz-Deblauwe, E., Winter, N., Paget, C., Girard, J.-P., Pham, C. T. N., Cougoule, C., Poincloux, R., Lamkanfi, M., … Planès, R. (2022). Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa. PLoS Pathogens, 18(7), e1010305. https://doi.org/10.1371/journal.ppat.1010305

Guillon A, Brea-Diakite D, Cezard A, Wacquiez A, Baranek T, Bourgeais J, Picou F, Vasseur V, Meyer L, Chevalier C, Auvet A, Carballido JM, Nadal Desbarats L, Dingli F, Turtoi A, Le Gouellec A, Fauvelle F, Donchet A, Crépin T, Hiemstra PS, Paget C, Loew D, Herault O, Naffakh N, Le Goffic R, Si-Tahar M. Host succinate inhibits influenza virus infection through succinylation and nuclear retention of the viral nucleoprotein. EMBO J. 2022 Jun 14;41(12):e108306. doi: 10.15252/embj.2021108306. Epub 2022 May 4. PMID: 35506364; PMCID: PMC9194747.

Fleurot I, López-Gálvez R, Barbry P, Guillon A, Si-Tahar M, Bähr A, Klymiuk N, Sirard JC, Caballero I. TLR5 signalling is hyper-responsive in porcine cystic fibrosis airways epithelium. J Cyst Fibros. 2022 Mar;21(2):e117-e121. doi: 10.1016/j.jcf.2021.08.002. Epub 2021 Aug 20. PMID: 34420900.

Ayari MG, Favetta P, Warszycki D, Vasseur V, Hervé V, Degardin P, Carbonnier B, Si-Tahar M, Agrofoglio LA. Molecularly Imprinted Hydrogels Selective to Ribavirin as New Drug Delivery Systems to Improve Efficiency of Antiviral Nucleoside Analogue: A Proof-of-Concept Study with Influenza A Virus. Macromol Biosci. 2022 Feb;22(2):e2100291. doi: 10.1002/mabi.202100291. Epub 2021 Nov 21. PMID: 34773718.

Baranek, T., de Amat Herbozo, C., Mallevaey, T., & Paget, C. (2022). Deconstructing iNKT cell development at single-cell resolution. Trends in Immunology, 43(7), 503‑512. https://doi.org/10.1016/j.it.2022.04.012

Guillon A, Brea-Diakite D, Cezard A, Wacquiez A, Baranek T, Bourgeais J, Picou F, Vasseur V, Meyer L, Chevalier C, Auvet A, Carballido JM, Nadal Desbarats L, Dingli F, Turtoi A, Le Gouellec A, Fauvelle F, Donchet A, Crépin T, Hiemstra PS, Paget C, Loew D, Herault O, Naffakh N, Le Goffic R, Si-Tahar M. Host succinate inhibits influenza virus infection through succinylation and nuclear retention of the viral nucleoprotein. EMBO J. 2022 Jun 14;41(12):e108306. doi: 10.15252/embj.2021108306. Epub 2022 May 4. PMID: 35506364; PMCID: PMC9194747.

Paget, C., Doz-Deblauwe, E., Winter, N., & Briard, B. (2022). Specific NLRP3 Inflammasome Assembling and Regulation in Neutrophils : Relevance in Inflammatory and Infectious Diseases. Cells, 11(7), 1188. https://doi.org/10.3390/cells11071188

Chesnay, A., Paget, C., Heuzé-Vourc’h, N., Baranek, T., & Desoubeaux, G. (2022). Pneumocystis Pneumonia : Pitfalls and Hindrances to Establishing a Reliable Animal Model. Journal of Fungi (Basel, Switzerland), 8(2), 129. https://doi.org/10.3390/jof8020129

Bruchard, M., Geindreau, M., Perrichet, A., Truntzer, C., Ballot, E., Boidot, R., Racoeur, C., Barsac, E., Chalmin, F., Hibos, C., Baranek, T., Paget, C., Ryffel, B., Rébé, C., Paul, C., Végran, F., & Ghiringhelli, F. (2022). Recruitment and activation of type 3 innate lymphoid cells promote antitumor immune responses. Nature Immunology, 23(2), 262‑274.

Cezard A, Fouquenet D, Vasseur V, Jeannot K, Launay F, Si-Tahar M, Hervé V. Poly-L-Lysine to Fight Antibiotic Resistances of Pseudomonas aeruginosa. Int J Mol Sci. 2023 Feb 2;24(3):2851. doi: 10.3390/ijms24032851. PMID: 36769174; PMCID: PMC9917869.

Richter, F., Paget, C., & Apetoh, L. (2023). STING-driven activation of T cells : Relevance for the adoptive cell therapy of cancer. Cell Stress, 7(11), 95‑104. https://doi.org/10.15698/cst2023.11.291

Giret, C., Dos Santos, Y., Blasco, H., Paget, C., Gonzalez, L., Tressel, N., Dieu, M., Bigot, A., Gissot, V., Audemard-Verger, A., & Maillot, F. (2023). No evidence for systemic low-grade inflammation in adult patients with early-treated phenylketonuria : The INGRAPH study. JIMD Reports, 64(6), 446‑452. https://doi.org/10.1002/jmd2.12366

Pitiot A, Ferreira M, Parent C, Boisseau C, Cortes M, Bouvart L, Paget C, Heuzé-Vourc’h N, Sécher T. Mucosal administration of anti-bacterial antibodies provide long-term cross-protection against Pseudomonas aeruginosa respiratory infection. Mucosal Immunol. 2023 Mar 28:S1933-0219(23)00021-1. doi: 10.1016/j.mucimm.2023.03.005.

Alarcan, H., Berthet, M., Suire, L., Colas, C., Gonzalez, L., Paget, C., Benz-de Bretagne, I., Piver, E., Vourc’h, P., Andres, C., Corcia, P., & Blasco, H. (2022). Inflammatory mediators, lipoproteins and apolipoproteins in early diagnosis of amyotrophic lateral sclerosis. SLAS Technology, 27(5), 327‑334. https://doi.org/10.1016/j.slast.2022.07.003

Santoni, K., Pericat, D., Gorse, L., Buyck, J., Pinilla, M., Prouvensier, L., Bagayoko, S., Hessel, A., Leon-Icaza, S. A., Bellard, E., Mazères, S., Doz-Deblauwe, E., Winter, N., Paget, C., Girard, J.-P., Pham, C. T. N., Cougoule, C., Poincloux, R., Lamkanfi, M., … Planès, R. (2022). Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa. PLoS Pathogens, 18(7), e1010305. https://doi.org/10.1371/journal.ppat.1010305

Baranek T, Lebrigand K, de Amat Herbozo C, Gonzalez L, Bogard G, Dietrich C, Magnone V, Boisseau C, Jouan Y, Trottein F, Si-Tahar M, Leite-de-Moraes M, Mallevaey T, Paget C. High Dimensional Single-Cell Analysis Reveals iNKT Cell Developmental Trajectories and Effector Fate Decision. Cell Rep. 2020 Sep 8;32(10):108116. doi: 10.1016/j.celrep.2020.108116. PMID: 32905761.

Jouan Y, Guillon A, Gonzalez L, Perez Y, Boisseau C, Ehrmann S, Ferreira M, Daix T, Jeannet R, François B, Dequin PF, Si-Tahar M, Baranek T, Paget C. Phenotypical and functional alteration of unconventional T cells in severe COVID-19 patients. J Exp Med. 2020 Dec 7;217(12):e20200872. doi: 10.1084/jem.20200872. PMID: 32886755; PMCID: PMC7472174.

Hassane M, Jouan Y, Creusat F, Soulard D, Boisseau C, Gonzalez L, Patin EC, Heuzé-Vourc’h N, Sirard JC, Faveeuw C, Trottein F, Si-Tahar M, Baranek T, Paget C. Interleukin-7 protects against bacterial respiratory infection by promoting IL-17A-producing innate T-cell response. Mucosal Immunol. 2020 Jan;13(1):128-139. doi: 10.1038/s41385-019-0212-y. Epub 2019 Oct 18. PMID: 31628425.

Lantier L, Poupée-Beaugé A, di Tommaso A, Ducournau C, Epardaud M, Lakhrif Z, Germon S, Debierre-Grockiego F, Mévélec MN, Battistoni A, Coënon L, Deluce-Kakwata-Nkor N, Velge-Roussel F, Beauvillain C, Baranek T, Lee GS, Kervarrec T, Touzé A, Moiré N, Dimier-Poisson I. Neospora caninum: a new class of biopharmaceuticals in the therapeutic arsenal against cancer. J Immunother Cancer. 2020 Nov;8(2):e001242. doi: 10.1136/jitc-2020-001242. PMID: 33257408; PMCID: PMC7705568.

Lau I, de Amat Herbozo C, Kuypers M, Lin Q, Paget C, Mallevaey T. Altered Innate-like T Cell Development in Vα14-Jα18 TCRα Transgenic Mice. Immunohorizons. 2020 Dec 15;4(12):797-808. doi: 10.4049/immunohorizons.2000100. PMID: 33323387.

Morello E, Pérez-Berezo T, Boisseau C, Baranek T, Guillon A, Bréa D, Lanotte P, Carpena X, Pietrancosta N, Hervé V, Ramphal R, Cenac N, Si-Tahar M. Pseudomonas aeruginosa Lipoxygenase LoxA Contributes to Lung Infection by Altering the Host Immune Lipid Signaling. Front Microbiol. 2019 Aug 14;10:1826

Guillon A, Darrouzain F, Heuze-Vourc’H N, Petitcollin A, Barc C, Vecellio L, Cormier B, Lanotte P, Sarradin P, Dequin PF, Paintaud G, Ehrmann S. Intra-tracheal amikacin spray delivery in healthy mechanically ventilated piglets. Pulm Pharmacol Ther. 2019 May 15:101807. doi: 10.1016/j.pupt.2019.101807. [Epub ahead of print]  

Georgel AF, Cayet D, Pizzorno A, Rosa-Calatrava M, Paget C, Sencio V, Dubuisson J, Trottein F, Sirard JC, Carnoy C. Toll-like receptor 5 agonist flagellin reduces influenza A virus replication independently of type I interferon and interleukin 22 and improves antiviral efficacy of oseltamivir. Antiviral Res. 2019 May 9;168:28-35. doi: 10.1016/j.antiviral.2019.05.002. [Epub ahead of print]

Mogilenko DA, Haas JT, L’homme L, Fleury S, Quemener S, Levavasseur M, Becquart C, Wartelle J, Bogomolova A, Pineau L, Molendi-Coste O, Lancel S, Dehondt H, Gheeraert C, Melchior A, Dewas C, Nikitin A, Pic S, Rabhi N, Annicotte JS, Oyadomari S, Velasco-Hernandez T, Cammenga J, Foretz M, Viollet B, Vukovic M, Villacreces A, Kranc K, Carmeliet P, Marot G, Boulter A, Tavernier S, Berod L, Longhi MP, Paget C, Janssens S, Staumont-Sallé D, Aksoy E, Staels B, Dombrowicz D. Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR. Cell. 2019 May 16;177(5):1201-1216.e19. doi: 10.1016/j.cell.2019.03.018. Epub 2019 Apr 25.

Sécher T, Dalonneau E, Ferreira M, Parent C, Azzopardi N, Paintaud G, Si-Tahar M, Heuzé-Vourc’h N. In a murine model of acute lung infection, airway administration of a therapeutic antibody confers greater protection than parenteral administration. J Control Release. 2019 Apr 11;303:24-33. doi: 10.1016/j.jconrel.2019.04.005. [Epub ahead of print]

Magnen M, Gueugnon F, Petit-Courty A, Baranek T, Sizaret D, Brewah YA, Humbles A, Si-Tahar M, Courty Y. Tissue kallikrein (KLK1) regulates alveolar macrophage apoptosis early in influenza virus infection. Am J Physiol Lung Cell Mol Physiol. 2019 Mar 25. doi: 10.1152/ajplung.00379.2018. [Epub ahead of print]

Guillon A, Pardessus J, Lhommet P, Parent C, Respaud R, Marchand D, Montharu J, De Monte M, Janiak P, Boixel C, Audat H, Huille S, Guillot E, Heuze-Vourc’h N. Exploring the fate of inhaled monoclonal antibody in the lung parenchyma by microdialysis. MAbs. 2019 Feb/Mar;11(2):297-304. doi: 10.1080/19420862.2018.1556081. Epub 2019 Feb 4.

Guillon A, Brea D, Luczka E, Hervé V, Hasanat S, Thorey C, Pérez-Cruz M, Hordeaux J, Mankikian J, Gosset P, Coraux C, Si-Tahar M. Inactivation of the interleukin-22 pathway in the airways of cystic fibrosis patients. Cytokine. 2019 Jan. doi: 10.1016/j.cyto.2018.10.015. Epub 2018 Oct 28

Paget C, Deng S, Soulard D, Priestman DA, Speca S, von Gerichten J, Speak AO, Saroha A, Pewzner-Jung Y, Futerman AH, Mallevaey T, Faveeuw C, Gu X, Platt FM, Sandhoff R, Trottein F. TLR9-mediated dendritic cell activation uncovers mammalian ganglioside species with specific ceramide backbones that activate invariant natural killer T cells. PLoS Biol. 2019 Mar 1;17(3):e3000169. doi: 10.1371/journal.pbio.3000169.

Paget C, Trottein F. Mechanisms of Bacterial Superinfection Post-influenza: A Role for Unconventional T Cells. Front Immunol. 2019 Mar 1;10:336. doi: 10.3389/fimmu.2019.00336. eCollection 2019. Review.

Bodet-Contentin L, Guillon A, Boulain T, Frat JP, Garot D, Le Pennec D, Vecellio L, Ehrmann S, Giraudeau B, Tavernier E, Dequin PF. Salbutamol Nebulization During Noninvasive Ventilation in Exacerbated Chronic Obstructive Pulmonary Disease Patients: A Randomized Controlled Trial. J Aerosol Med Pulm Drug Deliv. 2018 Dec 27. doi: 10.1089/jamp.2018.1484. [Epub ahead of print]

Laporte L, Hermetet C, Jouan Y, Gaborit C, Rouve E, Shea KM, Si-Tahar M, Dequin PF, Grammatico-Guillon L, Guillon A. Ten-year trends in intensive care admissions for respiratory infections in the elderly. Ann Intensive Care. 2018 Aug 15;8(1):84. doi: 10.1186/s13613-018-0430-6.

Guillon A, Fouquenet D, Morello E, Henry C, Georgeault S, Si-Tahar M, Hervé V. Treatment of Pseudomonas aeruginosa Biofilm Present in Endotracheal Tubes by Poly-l-Lysine. Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e00564-18. doi: 10.1128/AAC.00564-18.

Garcia M, Morello E, Garnier J, Barrault C, Garnier M, Burucoa C, Lecron JC, Si-Tahar M, Bernard FX, Bodet C. Pseudomonas aeruginosa flagellum is critical for invasion, cutaneous persistence and induction of inflammatory response of skin epidermis. Virulence. 2018;9(1):1163-1175. doi: 10.1080/21505594.2018.1480830.

Lawand M, Evnouchidou I, Baranek T, Montealegre S, Tao S, Drexler I, Saveanu L, Si-Tahar M, van Endert P. Impact of the TAP-like transporter in antigen presentation and phagosome maturation. Mol Immunol. 2018 Jun 23. pii: S0161-5890(18)30483-8. doi: 10.1016/j.molimm.2018.06.268. [Epub ahead of print]

Guillon A, Sécher T, Dailey LA, Vecellio L, de Monte M, Si-Tahar M, Diot P, Page CP, Heuzé-Vourc’h N. Insights on animal models to investigate inhalation therapy: Relevance for biotherapeutics. Int J Pharm. 2018 Jan 30;536(1):116-126. doi: 10.1016/j.ijpharm.2017.11.049. Epub 2017 Nov 24. Review.

Nunez N, Derré-Bobillot A, Gaubert S, Herry JM, Deschamps J, Wei Y, Baranek T, Si-Tahar M, Briandet R, Serror P, Archambaud C. Exploration of the role of the virulence factor ElrA during Enterococcus faecalis cell infection. Sci Rep. 2018 Jan 29;8(1):1749. doi: 10.1038/s41598-018-20206-6

Trottein F, Paget C. Natural Killer T Cells and Mucosal-Associated Invariant T Cells in Lung Infections. Front Immunol. 2018 Aug 2;9:1750. doi: 10.3389/fimmu.2018.01750. eCollection 2018. Review.

Jouan Y, Patin EC, Hassane M, Si-Tahar M, Baranek T, Paget C. Thymic Program Directing the Functional Development of γδT17 Cells. Front Immunol. 2018 May 8;9:981. doi: 10.3389/fimmu.2018.00981. eCollection 2018. Review.

Le Rouzic O, Pichavant M, Frealle E, Guillon A, Si-Tahar M, Gosset P. Th17 cytokines: novel potential therapeutic targets for COPD pathogenesis and exacerbations. Eur Respir J. 2017 Oct 12;50(4). pii: 1602434. doi: 10.1183/13993003.02434-2016.

Alessi MC, Cenac N, Si-Tahar M, Riteau B. FPR2: A Novel Promising Target for the Treatment of Influenza. Front Microbiol. 2017 Sep 5;8:1719. doi:10.3389/fmicb.2017.01719. eCollection 2017.

Magnen M, Gueugnon F, Guillon A, Baranek T, Thibault VC, Petit-Courty A, de Veer SJ, Harris J, Humbles AA, Si-Tahar M, Courty Y. Kallikrein-Related Peptidase 5 Contributes to H3N2 Influenza Virus Infection in Human Lungs. J Virol. 2017 Jul 27;91(16). pii: e00421-17. doi: 10.1128/JVI.00421-17.

Guarino C, Hamon Y, Croix C, Lamort AS, Dallet-Choisy S, Marchand-Adam S, Lesner A, Baranek T, Viaud-Massuard MC, Lauritzen C, Pedersen J, Heuzé-Vourc’h N, Si-Tahar M, Fıratlı E, Jenne DE, Gauthier F, Horwitz MS, Borregaard N, Korkmaz B. Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases. Biochem Pharmacol. 2017 May 1;131:52-67. doi: 10.1016/j.bcp.2017.02.009.

Demiselle J, Auchabie J, Beloncle F, Gatault P, Grangé S, Du Cheyron D, Dellamonica J, Boyer S, Beauport DT, Piquilloud L, Letheulle J, Guitton C, Chudeau N, Geri G, Fourrier F, Robert R, Guérot E, Boisramé-Helms J, Galichon P, Dequin PF, Lautrette A, Bollaert PE, Meziani F, Guillevin L, Lerolle N, Augusto JF. Patients with ANCA-associated vasculitis admitted to the intensive care unit with acute vasculitis manifestations: a retrospective and comparative multicentric study. Ann Intensive Care. 2017 Dec;7(1):39. doi: 10.1186/s13613-017-0262-9. Epub 2017 Apr 5.

Auvet A, Simundic AM, Guillon A. The preanalytical phase should be carefully assessed during the comparisons of point-of-care versus central laboratory measurements. Heart Lung. 2017 Sep – Oct;46(5):402-403. doi: 10.1016/j.hrtlng.2017.05.011. Epub 2017 Jul 19

Muller G, Mercier E, Vignon P, Henry-Lagarrigue M, Kamel T, Desachy A, Botoc V, Plantefève G, Frat JP, Bellec F, Quenot JP, Dequin PF, Boulain T; Clinical Research in Intensive Care and Sepsis (CRICS) Group. Prognostic significance of central venous-to-arterial carbon dioxide difference during the first 24 hours of septic shock in patients with and without impaired cardiac function. Br J Anaesth. 2017 Aug 1;119(2):239-248. doi: 10.1093/bja/aex131.

Nay MA, Auvet A, Mankikian J, Herve V, Dequin PF, Guillon A. Evaluation of a flexible bronchoscope prototype designed for bronchoscopy during mechanical ventilation: a proof-of-concept study. Anaesthesia. 2017 Jun;72(6):719-728. doi: 10.1111/anae.13839. Epub 2017 Mar 14.

Auvet A, Nay MA, Grammatico-Guillon L, Espitalier F, Dequin PF, Guillon A. Therapeutic decision-making process in the intensive care unit: role of biological point-of-care testing. Clin Chem Lab Med. 2017 Feb 1;55(2):e41-e43. doi: 10.1515/cclm-2016-0578.

Lascarrou JB, Boisrame-Helms J, Bailly A, Le Thuaut A, Kamel T, Mercier E, Ricard JD, Lemiale V, Colin G, Mira JP, Meziani F, Messika J, Dequin PF, Boulain T, Azoulay E, Champigneulle B, Reignier J; Clinical Research in Intensive Care and Sepsis (CRICS) Group. Video Laryngoscopy vs Direct Laryngoscopy on Successful First-Pass Orotracheal Intubation Among ICU Patients: A Randomized Clinical Trial. JAMA. 2017 Feb 7;317(5):483-493. doi: 10.1001/jama.2016.20603.

Saroha A, Pewzner-Jung Y, Ferreira NS, Sharma P, Jouan Y, Kelly SL, Feldmesser E, Merrill AH Jr, Trottein F, Paget C, Lang KS, Futerman AH. Critical Role for Very-Long Chain Sphingolipids in Invariant Natural Killer T Cell Development and Homeostasis. Front Immunol. 2017 Nov 1;8:1386. doi: 10.3389/fimmu.2017.01386. eCollection 2017.

Patin EC, Soulard D, Fleury S, Hassane M, Dombrowicz D, Faveeuw C, Trottein F, Paget C. Type I IFN receptor signalling controls IL-7-dependent accumulation and activity of protumoral IL-17A-producing γδT cells in breast cancer. Cancer Res. 2017 Oct 25. pii: canres.1416.2017. doi: 10.1158/0008-5472.CAN-17-1416. [Epub ahead of print]

Hassane M, Demon D, Soulard D, Fontaine J, Keller LE, Patin EC, Porte R, Prinz I, Ryffel B, Kadioglu A, Veening JW, Sirard JC, Faveeuw C, Lamkanfi M, Trottein F, Paget C. Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections. Mucosal Immunol. 2017 Jul;10(4):1056-1068. doi: 10.1038/mi.2016.113.

Le Gars M, Haustant M, Klezovich-Benard M, Paget C, Trottein F, Goossens PL, Tournier JN. iNKT cells: potential therapeutic targets to fight anthrax. Med Sci (Paris). 2017 May;33(5):488-490. doi: 10.1051/medsci/20173305010.

Baranek T, Morello E, Valayer A, Aimar RF, Bréa D, Henry C, Besnard AG, Dalloneau E, Guillon A, Dequin PF, Narni-Mancinelli E, Vivier E, Laurent F, Wei Y, Paget C, Si-Tahar M. FHL2 Regulates Natural Killer Cell Development and Activation during Streptococcus pneumoniae Infection. Front Immunol. 2017 Feb 13;8:123. doi: 10.3389/fimmu.2017.00123

Valayer A, Brea D, Lajoie L, Avezard L, Combes-Soia L, Labas V, Korkmaz B, Thibault G, Baranek T, Si-Tahar M. Neutrophils can disarm NK cell response through cleavage of NKp46. J Leukoc Biol. 2017 Jan;101(1):253-259. doi: 10.1189/jlb.3AB0316-140RR. Epub 2016 Sep 1.

Guillon A, Brea D, Morello E, Tang A, Jouan Y, Ramphal R, Korkmaz B, Perez-Cruz M, Trottein F, O’Callaghan RJ, Gosset P, Si-Tahar M. Pseudomonas aeruginosa proteolytically alters the interleukin 22-dependent lung mucosal defense. Virulence. 2016 Oct 28:1-11. doi: 10.1080/21505594.2016.1253658. [Epub ahead of print]

Henry CO, Dalloneau E, Pérez-Berezo MT, Plata C, Wu Y, Guillon A, Morello E, Aimar RF, Potier-Cartereau M, Esnard F, Coraux C, Boernchen C, Kiefmann R, Vandier C, Touqui L, Valverde MA, Cenac N, Si-Tahar M. In vitro and in vivo evidence for an inflammatory role of the calcium channel TRPV4 in lung epithelium – Potential involvement in cystic fibrosis. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 5. doi: 10.1152/ajplung.00442.2015.

Patin F, Baranek T, Vourc’h P, Nadal-Desbarats L, Goossens JF, Marouillat S, Dessein AF, Descat A, Hounoum BM, Bruno C, Watier H, Si-Tahar M, Leman S, Lecron JC, Andres CR, Corcia P, Blasco H. Combined Metabolomics and Transcriptomics Approaches to Assess the IL-6 Blockade as a Therapeutic of ALS: Deleterious Alteration of Lipid Metabolism. Neurotherapeutics. 2016 Jul 21.

Auvet A, Espitalier F, Grammatico-Guillon L, Nay MA, Elaroussi D, Laffon M, Andres CR, Legras A, Ehrmann S, Dequin PF, Gendrot C, Guillon A. Preanalytical conditions of point-of-care testing in the intensive care unit are decisive for analysis reliability. Annals of Intensive care. 2016 2016 Dec;6(1):57.

Nay MA, Auvet A, Guillon A. Fibreoptic bronchoscopy in mechanically ventilated ARDS patients – a reply. Anaesthesia. 2016 Jun;71(6):729. 

Nay MA, Mankikian J, Auvet A, Dequin PF, Guillon A. The effect of fibreoptic bronchoscopy in acute respiratory distress syndrome: experimental evidence from a lung model. Anaesthesia. 2016 Feb;71(2):185-91. 

Gueugnon F, Thibault VC, Kearley J, Petit-Courty A, Vallet A, Guillon A, Si-Tahar M, Humbles AA, Courty Y. Altered expression of the CCN genes in the lungs of mice in response to cigarette smoke exposure and viral and bacterial infections. Gene. 2016 Apr 11. 

Tcherniuk S, Cenac N, Comte M, Frouard J, Errazuriz-Cerda E, Galabov A, Morange PE, Vergnolle N, Si-Tahar M, Alessi MC, Riteau B. Formyl peptide receptor 2 plays a deleterious role during influenza A virus infections. J Infect Dis. 2016 Mar 30. 

Hamon Y, Legowska M, Hervé V, Dallet-Choisy S, Marchand-Adam S, Vanderlynden L, Demonte M, Williams R, Scott CJ, Si-Tahar M, Heuzé-Vourc’h N, Lalmanach G, Jenne DE, Lesner A, Gauthier F, Korkmaz B. Neutrophilic cathepsin C is maturated by a multi-step proteolytic process and secreted by activated cells during inflammatory lung diseases. J Biol Chem. 2016 Feb 16. 

Guillon A, Gueugnon F, Mavridis K, Dalloneau E, Jouan Y, Diot P, Heuzé-Vourc’h N, Courty Y, Si-Tahar M. Interleukin-22 receptor is overexpressed in nonsmall cell lung cancer and portends a poor prognosis. Eur Respir J. 2016 Apr;47(4):1277-80.

Blanc F, Furio L, Moisy D, Yen HL, Chignard M, Letavernier E, Naffakh N, Mok CK, Si-Tahar M. Targeting host calpain proteases decreases influenza A virus infection. Am J Physiol Lung Cell Mol Physiol. 2016 Jan 8. 

Moënne-Loccoz J, Cohen B, Laffon M, Guillon A. Hemodynamic collapse in prone position due to thoracic malformation. Intensive Care Med. 2015 Dec 22.

Guillon A, Vecellio L, de Monte M. Pulmonary Delivery of Dry Powders During Invasive Mechanical Ventilation: Innovations Are Required. J Aerosol Med Pulm Drug Deliv. 2015

Guillon A, Chevaleyre C, Barc C, Berri M, Adriaensen H, Lecompte F, Villemagne T, Pezant J, Delaunay R, Moënne-Loccoz J, Berthon P, Bähr A, Wolf E, Klymiuk N, Attucci S, Ramphal R, Sarradin P, Buzoni-Gatel D, Si-Tahar M, Caballero I. Computed Tomography (CT) Scanning Facilitates Early Identification of Neonatal Cystic Fibrosis Piglets. PLoS One. 2015 Nov 23;10(11):e0143459.

Guillon A., Jouan Y., Brea D., Gueugnon F., Dalloneau E., Baranek T., Henry C., Morello E., Renauld JC., Pichavant M., Gosset P., Courty Y., Diot P. and Si-Tahar M. Neutrophil proteases alter the interleukin-22-receptor-dependent lung antimicrobial defence. Eur Respir J. 2015 Aug 6. pii: ERJ-02151-2014.

Nay MA, Mankikian J, Garot D, Guillon A. Investigation of a cause-effect relationship between flexible bronchoscopy and pneumothorax in patients with severe ARDS. Eur. J. Anesthesia. 2015.

Borges BE, Appel MH, Cofré AR, Prado ML, Steclan CA, Esnard F, Zanata SM, Laurindo FR, Nakao LS. The flavo-oxidase QSOX1 supports vascular smooth muscle cell migration and proliferation: Evidence for a role in neointima growth. Biochim Biophys Acta. 2015 Jul;1852(7):1334-46.

Guillon A, Mercier E, Lanotte P, Haguenoer E, Darrouzain F, Barc C, Sarradin P, Si-Tahar M, Herzé-Vourc’h N, Diot P,Vecellio L. Aerosol Route to Administer Teicoplanin in Mechanical Ventilation: in Vitro Study, Lung Deposition and Pharmacokinetic Analyses in Pigs. J Aerosol Med Pulm Drug Deliv. 2015 Jan 23.

Boulain T, Boisrame-Helms J, Ehrmann S, Lascarrou JB, Bouglé A, Chiche A, Lakhal K, Gaudry S, Perbet S, Desachy A, Cabasson S, Geneau I, Courouble P, Clavieras N, Massanet PL, Bellec F, Falquet Y, Réminiac F, Vignon P, Dequin PF, Meziani F. Volume expansion in the first 4 days of shock: a prospective multicentre study in 19 French intensive care units. Intensive Care Med. 2015 Feb;41(2):248-56.

Guilleminault L, Azzopardi N, Arnoult C, Sobilo J, Hervé V, Montharu J, Guillon A, Andres C, Herault O, Le Pape A, Diot P, Lemarié E, Paintaud G, Gouilleux-Gruart V, Heuzé-Vourc’h N. Fate of inhaled monoclonal antibodies after deposition of aerosolized particles in the respiratory system. J Control Release. 2014 Dec 28;196:344-54. 

Hervé V, Rabbe N, Guilleminault L, Paul F, Schlick L, Azzopardi N, Duruisseaux M, Fouquenet D, Montharu J, Redini F, Paintaud G, Lemarié E, Cadranel J, Wislez M and Heuzé-Vourc’h N. (2014) VEGF neutralizing aerosol therapy in primary pulmonary adenocarcinoma with K-ras activating-mutations. MAbs. 2014;6(6):1638-48. 

Hervé V., Meudal H., Labas V., Rehault-Godbert S., Gautron J., Berges M., Guyot N., Delmas A.F., Nys Y., Landon C. Three-dimensional NMR Structure of Hen Egg Gallin (Chicken Ovodefensin) Reveals a New Variation of the beta-Defensin Fold. J Biol Chem 2014;289:7211-7220. 

Respaud R, Marchand D, Parent C, Pelat T, Thullier P, Tournamille JF, Viaud-Massuard MC, Diot P, Si-Tahar M, Vecellio L, Heuzé-Vourc’h N. Effect of formulation on the stability and aerosol performance of a nebulized antibody. MAbs. 2014 Aug 5;6(5). 

Si-Tahar M, Blanc F, Furio L, Chopy D, Balloy V, Lafon M, Chignard M, Fiette L, Langa F, Charneau P, Pothlichet J. Protective role of LGP2 in influenza virus pathogenesis. J Infect Dis. 2014 Jul 15;210(2):214-23. 

Mankikian J, Ehrmann S, Le Fol T, Barc C, Ferrandière M, Boulain T, Dequin PF, Guilleminault L, Guillon A. An evaluation of a new single-use flexible bronchoscope with a large suction channel: reliability of bronchoalveolar lavage in ventilated piglets and initial clinical experience. Anaesthesia. 2014 Jul;69(7):701-6 

Mankikian J, Favelle O, Guillon A, Guilleminault L, Cormier B, Jonville-Béra AP, Perrotin D, Diot P, Marchand-Adam S. Amiodarone-induced pulmonary toxicity: prognosis factors and outcome. Respir Med. 2014 Apr;108(4):638-46. 

Boulain T, Garot D, Vignon P, Lascarrou JB, Desachy A, Botoc V, Follin A, Frat JP, Bellec F, Quenot JP, Mathonnet A, Dequin PF; Clinical Research in Intensive Care and Sepsis Group. Prevalence of low central venous oxygen saturation in the first hours of intensive care unit admission and associated mortality in septic shock patients: a prospective multicentre study. Crit Care. 2014 Nov 6;18(6):609. 

Boulain T, Garot D, Vignon P, Lascarrou JB, Desachy A, Botoc V, Follin A, Frat JP, Bellec F, Quenot JP, Mathonnet A, Dequin PF ; Clinical Research in Intensive Care and Sepsis Group (Guillon A). Prevalence of low central venous oxygen saturation in the first hours of intensive care unit admission and associated mortality in septic shock patients: a prospective multicentre study. Crit Care. 2014 Nov 6;18(6):609. 

Asfar P, Meziani F, Hamel JF, Grelon F, Megarbane B, Anguel N, Mira JP, Dequin PF, Gergaud S, Weiss N, Legay F, Le Tulzo Y, Conrad M, Robert R, Gonzalez F, Guitton C, Tamion F, Tonnelier JM, Guezennec P, Van Der Linden T, Vieillard-Baron A, Mariotte E, Pradel G, Lesieur O, Ricard JD, Hervé F, du Cheyron D, Guerin C, Mercat A, Teboul JL, Radermacher P; SEPSISPAM Investigators (Guillon A). High versus low blood-pressure target in patients with septic shock. N Engl J Med. 2014 Apr 24;370(17):1583-93.

Contentin L., Guillon A., Garot D., Gaudy-Graffin C., Perrotin D. Acute respiratory distress syndrome secondary to human metapneumovirus infection in a young healthy adult. Intensive Care Med 2013;39:533-534. 

Dahan J., Nouet Y., Jouvion G., Levillayer F., Adib-Conquy M., Cassard-Doulcier A.M., Tebbi A., Blanc F., Remy L., Chen J., Cairo S., Werts C., Si-Tahar M., Tordjmann T., Buendia M.A., Wei Y. The LIM-only protein FHL2 activates NF-kappaB signaling in the control of liver regeneration and hepatocarcinogenesis. Mol Cell Biol 2013. 

Ivanov S., Renneson J., Fontaine J., Barthelemy A., Paget C., Fernandez E.M., Blanc F., De Trez C., Van Maele L., Dumoutier L., Huerre M.R., Eberl G., Si-Tahar M., Gosset P., Renauld J.C., Sirard J.C., Faveeuw C., Trottein F. Interleukin-22 Reduces Lung Inflammation during Influenza A Virus Infection and Protects against Secondary Bacterial Infection. J Virol 2013;87:6911-6924. 

Jordan S., Ruzsics Z., Mitrovic M., Baranek T., Arapovic J., Krmpotic A., Vivier E., Dalod M., Jonjic S., Dolken L., Koszinowski U.H. Natural Killer Cells Are Required for Extramedullary Hematopoiesis following Murine Cytomegalovirus Infection. Cell Host Microbe 2013;13:535-545. 

Manh T.P., Alexandre Y., Baranek T., Crozat K., Dalod M. Plasmacytoid, conventional and monocyte-derived dendritic cells undergo a profound and convergent genetic reprogramming during their maturation. Eur J Immunol 2013. 

Dubois AV, Midoux P, Gras D, Si-Tahar M, Bréa D, Attucci S, Khelloufi MK, Ramphal R, Diot P, Gauthier F, Hervé V. Poly-L-Lysine compacts DNA, kills bacteria, and improves protease inhibition in cystic fibrosis sputum. Am J Respir Crit Care Med. 2013 Sep 15;188(6):703-9. 

Réhault-Godbert S, Labas V, Helloin E, Hervé-Grépinet V, Slugocki C, Berges M, Bourin MC, Brionne A, Poirier JC, Gautron J, Coste F, Nys Y. Ovalbumin-related protein X is a heparin-binding ov-serpin exhibiting antimicrobial activities. J Biol Chem. 2013 Jun 14;288(24):17285-95. 

Mercier E, Darrouzain F, Montharu J, Guillon A, Diot P, Paitaud G, Vecellio L. Lung and serum teicoplanin concentration after aerosol and intravenous administration in a rat model. J Aerosol Med Pulm Drug Deliv. 2013, 27(4):306-12. 

Pham T, Combes A, Rozé H, Chevret S, Mercat A, Roch A, Mourvillier B, Ara-Somohano C, Bastien O, Zogheib E, Clavel M, Constan A, Marie Richard JC, Brun-Buisson C, Brochard L; REVA Research Network (Guillon A). Extracorporeal membrane oxygenation for pandemic influenza A(H1N1)-induced acute respiratory distress syndrome: a cohort study and propensity-matched analysis. Am J Respir Crit Care Med. 2013 Feb 1;187(3):276-85. 

Baranek T, Manh TP, Alexandre Y, Maqbool MA, Cabeza JZ, Tomasello E, Crozat K, Bessou G, Zucchini N, Robbins SH, Vivier E, Kalinke U, Ferrier P, Dalod M. Differential responses of immune cells to type I interferon contribute to host resistance to viral infection. Cell Host Microbe. 2012 Oct 18;12(4):571-84. 

Brea D., Meurens F., Dubois A.V., Gaillard J., Chevaleyre C., Jourdan M.L., Winter N., Arbeille B., Si-Tahar M., Gauthier F., Attucci S. The pig as a model for investigating the role of neutrophil serine proteases in human inflammatory lung diseases. Biochem J 2012;447:363-370.

Pernodet N, Hermetet F, Adami P, Vejux A, Descotes F, Borg C, Adams M, Pallandre JR, Viennet G, Esnard F, Jouvenot M, Despouy G. High expression of QSOX1 reduces tumorogenesis, and is associated with a better outcome for breast cancer patients. Breast Cancer Res. 2012 Oct 25;14(5):R136.

Dubois AV, Gauthier A, Bréa D, Varaigne F, Diot P, Gauthier F, Attucci S. Influence of DNA on the activities and inhibition of neutrophil serine proteases in cystic fibrosis sputum. Am J Respir Cell Mol Biol. 2012 Jul;47(1):80-6.

Maschalidi S, Hässler S, Blanc F, Sepulveda FE, Tohme M, Chignard M, van Endert P, Si-Tahar M, Descamps D, Manoury B. Asparagine Endopeptidase Controls Anti-Influenza Virus Immune Responses through TLR7 Activation. PLoS Pathog. 2012 Aug;8(8):e1002841.

Barbier D., Garcia-Verdugo I., Pothlichet J., Khazen R., Descamps D., Rousseau K., Thornton D., Si-Tahar M., Touqui L., Chignard M., Sallenave J.M. Influenza A induces the major secreted airway mucin MUC5AC in a protease-EGFR-extracellular regulated kinase-Sp1-dependent pathway. Am J Respir Cell Mol Biol 2012;47:149-157.

Muller G, Guillon A, Garot D, Mercier E, Perrotin D. Strategies for the withdrawal of extracorporeal membrane oxygenation for severe acute respiratory failure support: a new challenge? Anaesth Intensive Care. 2012 Mar;40(2):359.

Guillon A, Montharu J, Vecellio L, Schubnel V, Roseau G, Guillemain J, Diot P, de Monte M. Pulmonary delivery of dry powders to rats: Tolerability limits of an intra-tracheal administration model. Int J Pharm. 2012 Sep 15;434(1-2):481-7.

Paget C., Ivanov S., Fontaine J., Renneson J., Blanc F., Pichavant M., Dumoutier L., Ryffel B., Renauld J.C., Gosset P., Si-Tahar M., Faveeuw C., Trottein F. Interleukin-22 is produced by invariant natural killer T lymphocytes during influenza A virus infection: potential role in protection against lung epithelial damages. J Biol Chem 2012;287:8816-8829.

Eddabra L, Wenner T, El Btaouri H, Baranek T, Madoulet C, Cornillet-Lefebvre P, Morjani H. Arginine 482 to glycine mutation in ABCG2/BCRP increases etoposide transport and resistance to the drug in HEK-293 cells. Oncol Rep. 2012 Jan;27(1):232-7.

Mathieu A, Guillon A, Leyre S, Martin F, Fusciardi J, Laffon M.J. Aerosolized Lidocaine During Invasive Mechanical Ventilation: In Vitro Characterization and Clinical Efficiency to Prevent Systemic and Cerebral Hemodynamic Changes Induced by Endotracheal Suctioning in Head-injured Patients. Neurosurg Anesthesiol. 2012; 25(1):8-15.

Fichet J, Moreau L, Genée O, Legras A, Mercier E, Garot D, Dequin PF, Perrotin D. Feasibility of right ventricular longitudinal systolic function evaluation with transthoracic echocardiographic indices derived from tricuspid annular motion: a preliminary study in acute respiratory distress syndrome. Echocardiography. 2012 May;29(5):513-21.

Chopy D, Pothlichet J, Lafage M, Mégret F, Fiette L, Si-Tahar M, Lafon M. Ambivalent role of the innate immune response in rabies virus pathogenesis. J Virol. 2011 Jul;85(13):6657-68.

Guillon A, Montharu J, Cormier B, Vecellio L, Diot P, de Monte M. New insights into the pathophysiology of aspiration pneumonia. Br J Anaesth 2011 apr: 608-609

Paget C, Ivanov S, Fontaine J, Blanc F, Pichavant M, Renneson J, Bialecki E, Pothlichet J, Vendeville C, Barba-Spaeth G, Huerre MR, Faveeuw C, Si-Tahar M, Trottein F. Potential role of invariant NKT cells in the control of pulmonary inflammation and CD8+ T cell response during acute influenza A virus H3N2 pneumonia. J Immunol. 2011 May 15;186(10):5590-602.

Pothlichet J, Niewold TB, Vitour D, Solhonne B, Crow MK, Si-Tahar M. A loss-of-function variant of the antiviral molecule MAVS is associated with a subset of systemic lupus patients. EMBO Mol Med. 2011 Mar;3(3):142-52. 

Lepelley A, Louis S, Sourisseau M, Law HK, Pothlichet J, Schilte C, Chaperot L, Plumas J, Randall RE, Si-Tahar M, Mammano F, Albert ML, Schwartz O. Innate sensing of HIV-infected cells. PLoS Pathog. 2011 Feb;7(2):e1001284. 

Lakhal K, Ehrmann S, Benzekri-Lefèvre D, Runge I, Legras A, Dequin PF, Mercier E, Wolff M, Régnier B, Boulain T. Respiratory pulse pressure variation fails to predict fluid responsiveness in acute respiratory distress syndrome. Crit Care. 2011;15(2):R85. 

Garot D, Respaud R, Lanotte P, Simon N, Mercier E, Ehrmann S, Perrotin D, Dequin PF, Le Guellec C. Population pharmacokinetics of ceftriaxone in critically ill septic patients: a reappraisal. Br J Clin Pharmacol. 2011 Nov;72(5):758-67.