Sécher T, Cortes M, Boisseau C, Barba Goudiaby MT, Pitiot A, Parent C, Thomas M, Heuzé-Vourc’h N. Synergy between Lactobacillus murinus and anti-PcrV antibody delivered in the airways to boost protection against Pseudomonas aeruginosa. Mol Ther Methods Clin Dev. 2024 Aug 30;32(4):101330. doi: 10.1016/j.omtm.2024.101330. PMID: 39314638; PMCID: PMC11418128.

Blin T, Parent C, Pichon G, Guillon A, Jouan Y, Allouchi H, Aubrey N, Boursin F, Domain R, Korkmaz B, Sécher T, Heuzé-Vourc’h N. The proteolytic airway environment associated with pneumonia acts as a barrier for treatment with anti-infective antibodies. Eur J Pharm Biopharm. 2024 Feb;195:114163. doi: 10.1016/j.ejpb.2023.12.003. Epub 2023 Dec 10. PMID: 38086491.

Ferreira M, Ebia MI, Reckamp KL. Early dose reduction of osimertinib in advanced EGFR-mutated non-small cell lung cancer. Anticancer Drugs. 2024 Mar 22. doi: 10.1097/CAD.0000000000001609. Epub ahead of print. PMID: 38527329.

Maia AR, Cezard A, Fouquenet D, Vasseur V, Briard B, Sirard J-C, Si-Tahar M, Hervé V. Preventive nasal administration of flagellin restores antimicrobial effect of gentamicin and protects against a multidrug-resistant strain of Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2024 May 2;68(5):e0136123. doi: 10.1128/aac.01361-23. Epub 2024 Mar 25. PMID: 38526073; PMCID: PMC11064517.

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Reynard O, Montharu J, Iampietro M, Gonzalez C, Le Guellec S, Horvat B, Vecellio L. Setup of Aerosol Delivery System to Prevent Measles Virus Infection in Nonhuman Primate Model. Methods Mol Biol. 2024;2808:167-175. doi: 10.1007/978-1-0716-3870-5_13. PMID: 38743370.

Cabrera M, Le Pennec D, Le Guellec S, Pardessus J, Ehrmann S, MacLoughlin R, Heuzé-Vourc’h N, Vecellio L. Influence of mesh nebulizer characteristics on aerosol delivery in non-human primates. Eur J Pharm Sci. 2023 Dec 1;191:106606. doi: 10.1016/j.ejps.2023.106606. Epub 2023 Oct 11. PMID: 37832856.

Dugernier J, Le Pennec D, Maerckx G, Allimonnier L, Hesse M, Castanares-Zapatero D, Depoortere V, Vecellio L, Reychler G, Michotte JB, Goffette P, Docquier MA, Raftopoulos C, Jamar F, Laterre PF, Ehrmann S, Wittebole X. Inhaled drug delivery: a randomized study in intubated patients with healthy lungs. Ann Intensive Care. 2023 Dec 11;13(1):125. doi: 10.1186/s13613-023-01220-y. PMID: 38072870; PMCID: PMC10710976.

Ferreira M, Redman MW, Reckamp KL. Moving Toward Rationale Phase 3 Designs for Advanced NSCLC. J Thorac Oncol. 2023 Dec;18(12):1629-1631. doi: 10.1016/j.jtho.2023.09.1439. PMID: 37993216.

Sécher, T., Heuzé-Vourc’h, N. (2023). Pulmonary Delivery of Antibody for the Treatment of Respiratory Diseases. In: Lam, J., Kwok, P.C.L. (eds) Respiratory Delivery of Biologics, Nucleic Acids, and Vaccines. AAPS Introductions in the Pharmaceutical Sciences, vol 8. Springer, Cham. https://doi.org/10.1007/978-3-031-47567-2_2

Sécher T, Heuzé-Vourc’h N. Barriers for orally inhaled therapeutic antibodies. Expert Opin Drug Deliv. 2023 Aug 25:1-14. doi: 10.1080/17425247.2023.2249821. Epub ahead of print. PMID: 37609943.

Viollet S, Enouf E, Picot J, Noël L, Huet S, Le Pennec D, Sécher T, Heuzé-Vourc’h N, Kitten O, Cinier M. Inhalable Nanofitin demonstrates high neutralization of SARS-CoV-2 virus via direct application in respiratory tract. Mol Ther. 2023 Aug 24:S1525-0016(23)00442-2. doi: 10.1016/j.ymthe.2023.08.010. Epub ahead of print. PMID: 37652011.

Creppy J, Cabrera M, Kahlaoui N, Pardessus J, Lemaitre J, Naninck T, Delache B, Roseau G, Ducancel F, Vecellio L. Comparison of Aerosol Deposition Between a Cynomolgus Macaque and a 3D Printed Cast Model of the Animal. Pharm Res. 2023 Jan 18:1–11. doi: 10.1007/s11095-022-03466-w. Epub ahead of print. PMID: 36653519; PMCID: PMC9848713.

Cezard A, Fouquenet D, Vasseur V, Jeannot K, Launay F, Si-Tahar M, Hervé V. Poly-L-Lysine to Fight Antibiotic Resistances of Pseudomonas aeruginosa. Int J Mol Sci. 2023 Feb 2;24(3):2851. doi: 10.3390/ijms24032851. PMID: 36769174; PMCID: PMC9917869.

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Pitiot A, Ferreira M, Parent C, Boisseau C, Cortes M, Bouvart L, Paget C, Heuzé-Vourc’h N, Sécher T. Mucosal administration of anti-bacterial antibodies provide long-term cross-protection against Pseudomonas aeruginosa respiratory infection. Mucosal Immunol. 2023 Mar 28:S1933-0219(23)00021-1. doi: 10.1016/j.mucimm.2023.03.005.

Cerfeuillet V, Allimonnier L, Le Guellec S, Ménard L, Bokov P, Plantier L. Association of forced oscillation technique measurements with respiratory system compliance and resistance in a 2-compartment physical model. Respir Med Res. 2023 Nov;84:101027. doi: 10.1016/j.resmer.2023.101027. Epub 2023 May 13. PMID: 37717385.

Mergault C, Lisée F, Tiroille V, Magnien M, Parent C, Lenga Mabonda W, Sizaret D, Jaillet M, Crestani B, Marchand-Adam S, Plantier L. Inhibition of the Arp2/3 complex represses human lung myofibroblast differentiation and attenuates bleomycin-induced pulmonary fibrosis. Br J Pharmacol. 2022 Jan;179(1):125-140. doi: 10.1111/bph.15675. Epub 2021 Nov 15. PMID: 34453744.

Chesnay A, Paget C, Heuzé-Vourc’h N, Baranek T, Desoubeaux G. Pneumocystis Pneumonia: Pitfalls and Hindrances to Establishing a Reliable Animal Model. J Fungi (Basel). 2022 Jan 27;8(2):129. doi: 10.3390/jof8020129. PMID: 35205883; PMCID: PMC8877242.

Gangneux JP, Dannaoui E, Fekkar A, Luyt CE, Botterel F, De Prost N, Tadié JM, Reizine F, Houzé S, Timsit JF, Iriart X, Riu-Poulenc B, Sendid B, Nseir S, Persat F, Wallet F, Le Pape P, Canet E, Novara A, Manai M, Cateau E, Thille AW, Brun S, Cohen Y, Alanio A, Mégarbane B, Cornet M, Terzi N, Lamhaut L, Sabourin E, Desoubeaux G, Ehrmann S, Hennequin C, Voiriot G, Nevez G, Aubron C, Letscher-Bru V, Meziani F, Blaize M, Mayaux J, Monsel A, Boquel F, Robert-Gangneux F, Le Tulzo Y, Seguin P, Guegan H, Autier B, Lesouhaitier M, Pelletier R, Belaz S, Bonnal C, Berry A, Leroy J, François N, Richard JC, Paulus S, Argaud L, Dupont D, Menotti J, Morio F, Soulié M, Schwebel C, Garnaud C, Guitard J, Le Gal S, Quinio D, Morcet J, Laviolle B, Zahar JR, Bougnoux ME. Fungal infections in mechanically ventilated patients with COVID-19 during the first wave: the French multicentre MYCOVID study. Lancet Respir Med. 2022 Feb;10(2):180-190. doi: 10.1016/S2213-2600(21)00442-2. Epub 2021 Nov 26. PMID: 34843666; PMCID: PMC8626095.

Sécher T, Bodier-Montagutelli E, Parent C, Bouvart L, Cortes M, Ferreira M, MacLoughlin R, Ilango G, Schmid O, Respaud R, Heuzé-Vourc’h N. Aggregates Associated with Instability of Antibodies during Aerosolization Induce Adverse Immunological Effects. Pharmaceutics. 2022 Mar 18;14(3):671. doi: 10.3390/pharmaceutics14030671. PMID: 35336045; PMCID: PMC8949695.

Reidy L, Desoubeaux G, Cardenas J, Seither J, Kahl K, Chauvin D, Adkesson M, Govett P, Aitken-Palmer C, Stadler C, Tocidlowski M, Sirpenski G, Bronson E, Cray C. Detection of Gliotoxin but not bis(methyl)gliotoxin in plasma from birds with confirmed and probable aspergillosis. J Zoo Wild Med. 2022 Mar;53(1):60-69. doi: 10.1638/2021-0070. PMID: 35339150.

Al Ojaimi Y, Blin T, Lamamy J, Gracia M, Pitiot A, Denevault-Sabourin C, Joubert N, Pouget JP, Gouilleux-Gruart V, Heuzé-Vourc’h N, Lanznaster D, Poty S, Sécher T. Therapeutic antibodies – natural and pathological barriers and strategies to overcome them. Pharmacol Ther. 2022 May;233:108022. doi: 10.1016/j.pharmthera.2021.108022. Epub 2021 Oct 20. PMID: 34687769; PMCID: PMC8527648.

Thorel M, Mateos-Hernandez L, Mulot B, Azzouni MN, Hodžić A, Gaillot H, Ruel Y, Desoubeaux G, Delaye JB, Obregon D, Wu-Chuang A, de la Fuente J, Bermúdez-Humarán LG, Risco-Castillo V, Leclerc A, Cabezas-Cruz A. Assessment of the Safety and Efficacy of an Oral Probiotic-Based Vaccine Against Aspergillus Infection in Captive-Bred Humboldt Penguins (Spheniscus humboldti). Front Immunol. 2022 May 13;13:897223. doi: 10.3389/fimmu.2022.897223. PMID: 35634323; PMCID: PMC9137413.

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Desoubeaux G, Cray C, Chesnay A. Challenges to establish the diagnosis of aspergillosis in non-laboratory animals: looking for alternatives in veterinary medicine and demonstration of feasibility through two concrete examples in penguins and dolphins. Front Cell Infect Microbiol. 2022 Jul 19;12:757200. doi: 10.3389/fcimb.2022.757200. PMID: 35928207; PMCID: PMC9345302.

Cateau E, Leclerc A, Cartier N, Valsecchi I, Bailly É, Le Senechal R, Becerra M, Le Gallou B, Lavergne RA, Chesnay A, Robin JP, Cray C, Goddard N, Thorel M, Guillot J, Mulot B, Desoubeaux G. Aspergillosis in a colony of Humboldt penguins (Spheniscus humboldti) under managed care: a clinical and environmental investigation in a French zoological park. Med Mycol. 2022 Jul 9;60(7):myac046. doi: 10.1093/mmy/myac046. PMID: 35713494.

Pitiot A, Heuzé-Vourc’h N, Sécher T. Alternative Routes of Administration for Therapeutic Antibodies-State of the Art. Antibodies (Basel). 2022 Aug 26;11(3):56. doi: 10.3390/antib11030056. PMID: 36134952; PMCID: PMC9495858.

Reynard O, Gonzalez C, Dumont C, Iampietro M, Ferren M, Le Guellec S, Laurie L, Mathieu C, Carpentier G, Roseau G, Bovier FT, Zhu Y, Le Pennec D, Montharu J, Addetia A, Greninger AL, Alabi CA, Brisebard E, Moscona A, Vecellio L, Porotto M, Horvat B. Nebulized fusion inhibitory peptide protects cynomolgus macaques from measles virus infection. Nat Commun. 2022 Oct 28;13(1):6439. doi: 10.1038/s41467-022-33832-6. PMID: 36307480; PMCID: PMC9616412.

Chesnay A, Bailly É, Cosson L, Flament T, Desoubeaux G. Advent of elexacaftor/tezacaftor/ivacaftor for cystic fibrosis treatment: What consequences on Aspergillus-related diseases? Preliminary insights. J Cyst Fibros. 2022 Nov;21(6):1084-1085. doi: 10.1016/j.jcf.2022.09.007. Epub 2022 Sep 21. PMID: 36151024.

Mayor A, Thibert B, Huille S, Bensaid F, Respaud R, Audat H, Heuzé-Vourc’h N. Inhaled IgG1 antibodies: The buffering system is an important driver of stability during mesh-nebulization. Eur J Pharm Biopharm. 2022 Dec;181:173-182. doi: 10.1016/j.ejpb.2022.11.006. Epub 2022 Nov 14. PMID: 36395981.

Blin T, Flament T, Mankikian J, Chambellan A, Marchand-Adam S, Plantier L. Impulse oscillometry and spirometry measurements relative to personal best values at the time of acute exacerbations of cystic fibrosis in adults. Clin Physiol Funct Imaging. 2021 Jan;41(1):76-84. doi: 10.1111/cpf.12668. Epub 2020 Oct 23. PMID: 33010097.

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Mayor A, Chesnay A, Desoubeaux G, Ternant D, Heuzé-Vourc’h N, Sécher T. Therapeutic Antibodies for the Treatment of Respiratory Tract Infections-Current Overview and Perspectives. Vaccines (Basel). 2021 Feb 13;9(2):151. doi: 10.3390/vaccines9020151. PMID: 33668613; PMCID: PMC7917879.

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Le Guellec S, Ehrmann S, Vecellio L. In vitro – in vivo correlation of intranasal drug deposition. Adv Drug Deliv Rev. 2021 Mar;170:340-352. doi: 10.1016/j.addr.2020.09.002. Epub 2020 Sep 10. PMID: 32918968.

Legué S, Marchand-Adam S, Plantier L, Bayeh BA, Morel H, Mangiapan G, Flament T. ThOracic Ultrasound in Idiopathic Pulmonary Fibrosis Evolution (TOUPIE): research protocol of a multicentric prospective study. BMJ Open. 2021 Mar 25;11(3):e039078. doi: 10.1136/bmjopen-2020-039078. PMID: 33766834; PMCID: PMC7996371.

Desgrouas M, Ehrmann S. Inhaled antibiotics during mechanical ventilation-why it will work, Ann Transl Med. 2021 Apr;9(7):598. doi: 10.21037/atm-20-3686

Salmanton-García J, Sprute R, Stemler J, Bartoletti M, Dupont D, Valerio M, Garcia-Vidal C, Falces-Romero I, Machado M, de la Villa S, Schroeder M, Hoyo I, Hanses F, Ferreira-Paim K, Giacobbe DR, Meis JF, Gangneux JP, Rodríguez-Guardado A, Antinori S, Sal E, Malaj X, Seidel D, Cornely OA, Koehler P; FungiScope European Confederation of Medical Mycology/The International Society for Human and Animal Mycology Working Group. COVID-19-Associated Pulmonary Aspergillosis, March-August 2020. Emerg Infect Dis. 2021;27(4):1077-1086. doi: 10.3201/eid2704.204895. Epub 2021 Feb 4. PMID: 33539721; PMCID: PMC8007287.

Ferreira M, Secher T, Heuze-Vourc’H N, Reckamp KL. Immune Checkpoint and Anti-Angiogenic Antibodies for the Treatment of Non-Small Cell Lung Cancer in the European Union and United States. Pharmaceutics. 2021 Jun 21;13(6):912. doi: 10.3390/pharmaceutics13060912. PMID: 34205484; PMCID: PMC8234109.

Danion F, Letscher-Bru V, Guitard J, Sitbon K, Dellière S, Angoulvant A, Desoubeaux G, Botterel F, Bellanger AP, Gargala G, Uhel F, Bougnoux ME, Gerber V, Michel J, Cornu M, Bretagne S, Lanternier F; COVID-Mucor study group. Coronavirus Disease 2019-Associated Mucormycosis in France: A Rare but Deadly Complication. Open Forum Infect Dis. 2021 Nov 6;9(2):ofab566. doi: 10.1093/ofid/ofab566. PMID: 35071681; PMCID: PMC8773954.

Ehrmann S, Li J, Ibarra-Estrada M, Perez Y, Pavlov I, McNicholas B, Roca O, Mirza S, Vines D, Garcia-Salcido R, Aguirre-Avalos G, Trump MW, Nay MA, Dellamonica J, Nseir S, Mogri I, Cosgrave D, Jayaraman D, Masclans JR, Laffey JG, Tavernier E; Awake Prone Positioning Meta-Trial Group. Awake prone positioning for COVID-19 acute hypoxaemic respiratory failure: a randomised, controlled, multinational, open-label meta-trial. Lancet Respir Med. 2021 Dec;9(12):1387-1395. doi: 10.1016/S2213-2600(21)00356-8. Epub 2021 Aug 20. PMID: 34425070; PMCID: PMC8378833.

Hassane M, Jouan Y, Creusat F, Soulard D, Boisseau C, Gonzalez L, Patin EC, Heuzé-Vourc’h N, Sirard JC, Faveeuw C, Trottein F, Si-Tahar M, Baranek T, Paget C. Interleukin-7 protects against bacterial respiratory infection by promoting IL-17A-producing innate T-cell response. Mucosal Immunol. 2020 Jan;13(1):128-139.

Khayath N, Doyen V, Gherasim A, Radu C, Choual I, Beck N, Jacob A, Schoettel F, Vecellio L, Domis N, de Blay F. Validation of Strasbourg environmental exposure chamber (EEC) ALYATEC® in mite allergic subjects with asthma. J Asthma. 2020 Feb;57(2):140-148. doi: 10.1080/02770903.2018.1563902. Epub 2019 Mar 28. PMID: 30919704.

Ehrmann S, Schmid O, Darquenne C, Rothen-Rutishauser B, Sznitman J, Yang L, Barosova H, Vecellio L, Mitchell J, Heuze-Vourc’h N. Innovative preclinical models for pulmonary drug delivery research. Expert Opin Drug Deliv. 2020 Apr;17(4):463-478. doi: 10.1080/17425247.2020.1730807. Epub 2020 Feb 23. PMID: 32057260; PMCID: PMC8083945.

Li J, Fink JB, Ehrmann S. High-flow nasal cannula for COVID-19 patients: low risk of bio-aerosol dispersion. Eur Respir J. 2020 May 14;55(5):2000892. doi: 10.1183/13993003.00892-2020. PMID: 32299867; PMCID: PMC7163690.

Desoubeaux G, Lemaignen A, Ehrmann S. Scientific rationale for inhaled caspofungin to treat Pneumocystis pneumonia: A therapeutic innovation likely relevant to investigate in a near future…. Int J Infect Dis. 2020 Jun;95:464-467. doi: 10.1016/j.ijid.2020.03.029. Epub 2020 Mar 16. PMID: 32194238.

Sécher T, Bodier-Montagutelli E, Guillon A, Heuzé-Vourc’h N. Correlation and clinical relevance of animal models for inhaled pharmaceuticals and biopharmaceuticals. Adv Drug Deliv Rev. 2020 Dec;167:148-169. doi: 10.1016/j.addr.2020.06.029. Epub 2020 Jul 6. PMID: 32645479.

Bodier-Montagutelli E, Respaud R, Perret G, Baptista L, Duquenne P, Heuzé-Vourc’h N, Vecellio L. Protein stability during nebulization: Mind the collection step! Eur J Pharm Biopharm. 2020 Jul;152:23-34. doi: 10.1016/j.ejpb.2020.04.006. Epub 2020 Apr 11. PMID: 32289493.

Le Guellec S, Allimonnier L, Heuzé-Vourc’h N, Cabrera M, Ossant F, Pourchez J, Vecellio L, Plantier L. Low-Frequency Intrapulmonary Percussive Ventilation Increases Aerosol Penetration in a 2-Compartment Physical Model of Fibrotic Lung Disease. Front Bioeng Biotechnol. 2020 Aug 28;8:1022. doi: 10.3389/fbioe.2020.01022. PMID: 32984287; PMCID: PMC7483496.

Blasco H, Bessy C, Plantier L, Lefevre A, Piver E, Bernard L, Marlet J, Stefic K, Benz-de Bretagne I, Cannet P, Lumbu H, Morel T, Boulard P, Andres CR, Vourc’h P, Hérault O, Guillon A, Emond P. The specific metabolome profiling of patients infected by SARS-COV-2 supports the key role of tryptophan-nicotinamide pathway and cytosine metabolism. Sci Rep. 2020 Oct 8;10(1):16824. doi: 10.1038/s41598-020-73966-5. PMID: 33033346; PMCID: PMC7544910.

Sécher T, Mayor A, Heuzé-Vourc’h N, Inhalation of Immuno-Therapeutics/-Prophylactics to Fight Respiratory Tract Infections: An Appropriate Drug at the Right Place! Front Immunol. 2019 Nov 29;10:2760.

Desoubeaux G, Pelegrin M, Monoclonal antibodies in infectious diseases: new partners in the therapeutic arsenal, Med Sci (Paris). 2019 Dec;35(12):1008-1013.

Beck A, Guillarme D, Fleury-Souverain S, Bodier-Montagutelli E, Respaud R, Biosimilar monoclonal antibodies: comparative study of analytical and functional quality, Med Sci (Paris). 2019 Dec;35(12):1146-1152.

Montigaud Y, Périnel-Ragey S, Plantier L, Leclerc L, Goy C, Clotagatide A, Prévôt N, Pourchez J, Development of an ex vivo preclinical respiratory model of idiopathic pulmonary fibrosis for aerosol regional studies, Sci Rep. 2019 Nov 29;9(1):17949

Desoubeaux G, Chesnay A, Mercier V, Bras-Cachinho J, Moshiri P, Eymieux S, De Kyvon MA, Lemaignen A, Goudeau A, Bailly É, Combination of β-(1, 3)-D-glucan testing in serum and qPCR in nasopharyngeal aspirate for facilitated diagnosis of Pneumocystis jirovecii pneumonia, Mycoses. 2019 Nov;62(11):1015-1022.

Le Pennec D, Baravalle-Einaudi M, Dupont C, Vecellio L, Dubus JC; GRAM (Aerosols and Cystic Fibrosis Workgroup of the French Cystic Fibrosis Society). Cystic fibrosis in the modern therapeutic era: Give the shower a thought! J Cyst Fibros. 2019 Nov;18(6):e56-e57.

Chrystyn H, Audibert R, Keller M, Quaglia B, Vecellio L, Roche N, Real-life inhaler adherence and technique: Time to get smarter! Respir Med. 2019 Oct – Nov;158:24-32.

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Thille AW, Muller G, Gacouin A, Coudroy R, Decavèle M, Sonneville R, Beloncle F, Girault C, Dangers L, Lautrette A, Cabasson S, Rouzé A, Vivier E, Le Meur A, Ricard JD, Razazi K, Barberet G, Lebert C, Ehrmann S, Sabatier C, Bourenne J, Pradel G, Bailly P, Terzi N, Dellamonica J, Lacave G, Danin PÉ, Nanadoumgar H, Gibelin A, Zanre L, Deye N, Demoule A, Maamar A, Nay MA, Robert R, Ragot S, Frat JP; HIGH-WEAN Study Group and REVA Research Network, Effect of Postextubation High-Flow Nasal Oxygen With Noninvasive Ventilation vs High-Flow Nasal Oxygen Alone on Reintubation Among Patients at High Risk of Extubation Failure: A Randomized Clinical Trial, JAMA. 2019 Oct 2.

Coudroy R, Frat JP, Ehrmann S, Pène F, Terzi N, Decavèle M, Prat G, Garret C, Contou D, Bourenne J, Gacouin A, Girault C, Dellamonica J, Malacrino D, Labro G, Quenot JP, Herbland A, Jochmans S, Devaquet J, Benzekri D, Vivier E, Nseir S, Colin G, Thévenin D, Grasselli G, Assefi M, Guerin C, Bougon D, Lherm T, Kouatchet A, Ragot S, Thille AW; and the REVA Network, High-flow nasal oxygen therapy alone or with non-invasive ventilation in immunocompromised patients admitted to ICU for acute hypoxemic respiratory failure: the randomised multicentre controlled FLORALI-IM protocol. BMJ Open. 2019 Aug 10;9(8):e029798.

Guillon A, Darrouzain F, Heuzé-Vourc’h N, Petitcollin A, Barc C, Vecellio L, Cormier B, Lanotte P, Sarradin P, Dequin PF, Paintaud G, Ehrmann S, Intra-tracheal amikacin spray delivery in healthy mechanically ventilated piglets, Pulm Pharmacol Ther. 2019 Aug;57:101807.

Sécher T, Dalonneau E, Ferreira M, Parent C, Azzopardi N, Paintaud G, Si-Tahar M, Heuzé-Vourc’h N, In a murine model of acute lung infection, airway administration of a therapeutic antibody confers greater protection than parenteral administration, J Control Release. 2019 Jun 10;303:24-33.

Bodet-Contentin L, Guillon A, Boulain T, Frat JP, Garot D, Le Pennec D, Vecellio L, Ehrmann S, Giraudeau B, Tavernier E, Dequin PF, Salbutamol Nebulization During Noninvasive Ventilation in Exacerbated Chronic Obstructive Pulmonary Disease Patients: A Randomized Controlled Trial. J Aerosol Med Pulm Drug Deliv. 2019 Jun;32(3):149-155.

Desoubeaux G, Piqueras MDC, Le-Bert C, Fravel V, Clauss T, Delaune AJ, Daniels R, Jensen ED, Flower JE, Bossart GD, Bhattacharya SK, Cray C, Labeled quantitative mass spectrometry to study the host response during aspergillosis in the common bottlenose dolphin (Tursiops truncatus), Vet Microbiol. 2019 May;232:42-49.

Khayath N, Radu C, Choual I, Jilani S, Vecellio L, Domis N, De Blay F, Environmental exposure chambers (EEC): A novel tool for pathophysiological and pharmaceutical research, Rev Mal Respir. 2018 Apr;35(4):390-402.

Frat JP, Ricard JD, Quenot JP, Pichon N, Demoule A, Forel JM, Mira JP, Coudroy R, Berquier G, Voisin B, Colin G, Pons B, Danin PE, Devaquet J, Prat G, Clere-Jehl R, Petitpas F, Vivier E, Razazi K, Nay MA, Souday V, Dellamonica J, Argaud L, Ehrmann S, Gibelin A, Girault C, Andreu P, Vignon P, Dangers L, Ragot S, Thille AW; FLORALI-2 study group; REVA network, Non-invasive ventilation versus high-flow nasal cannula oxygen therapy with apnoeic oxygenation for preoxygenation before intubation of patients with acute hypoxaemic respiratory failure: a randomised, multicentre, open-label trial, Lancet Respir Med. 2019 Apr;7(4):303-312.

Chauvin D, Hust M, Schütte M, Chesnay A, Parent C, Moreira GMSG, Arroyo J, Sanz AB, Pugnière M, Martineau P, Chandenier J, Heuzé-Vourc’h N, Desoubeaux G, Targeting Aspergillus fumigatus Crf Transglycosylases With Neutralizing Antibody Is Relevant but Not Sufficient to Erase Fungal Burden in a Neutropenic Rat Model, Front Microbiol. 2019 Mar 26;10:600.

Ponsoye P, Vecellio L, Espitalier F, Remerand F, Laffon M, Pressurised metered-dose inhaler for beta-2 agonist delivery during intraoperative bronchospasm: comparison of different administration methods, British Journal of Anaesthesia, 2019

Kryza T, Parent C, Pardessus J, Petit A, Burlaud-Gaillard J, Reverdiau P, Iochmann S, Labas V, Courty Y, Heuzé-Vourc’h N, Human kallikrein-related peptidase 12 stimulates endothelial cell migration by remodeling the fibronectin matrix, Sci Rep. 2018

Desoubeaux G, Rodriguez M, Bronson E, Sirpenski G, Cray C, Application of 3-hydroxybutyrate measurement and plasma protein electrophoresis in the diagnosis of aspergillosis in african penguins (spheniscus demersus), J Zoo Wildl Med. 2018

Bodier-Montagutelli E, Mayor A, Vecellio L, Respaud R, Heuzé-Vourc’h N, Designing inhaled protein therapeutics for topical lung delivery: what are the next steps? Expert Opin Drug Deliv. 2018

Sécher T, Guilleminault L, Reckamp K, Amanam I, Plantier L, Heuzé-Vourc’h N, Therapeutic antibodies: A new era in the treatment of respiratory diseases? Pharmacol Ther. 2018

Cadena Castaneda D, Dhommée C, Baranek T, Dalloneau E, Lajoie L, Valayer A, Arnoult C, Dematté MV, Fouquenet D, Parent C, Heuzé-Vourc’h N, and Gouilleux-Gruart V, Lack of FcRn Impairs Natural Killer Cell Development and Functions in the Tumor Microenvironment, Front Immunol. 2018

Guillon A, Sécher T, Dailey LA, Vecellio L, De Monte M, Si-Tahar M, Diot P, Page CP, Heuzé-Vourc’h N., Insights on animal models to investigate inhalation therapy: Relevance for biotherapeutics, Int J Pharm. 2018

Desoubeaux G, Bailly É, Guillaume C, De Kyvon MA, Tellier AC, Morange V, Bernard L, Salamé E, Quentin R, Chandenier J., Candida auris in contemporary mycology labs: A few practical tricks to identify it reliably according to one recent French experience, J Mycol Med. 2018

Khayath N, Radu C, Choual I, Jilani S, Vecellio L, Domis N, De Blay F, Les chambres d’exposition environnementale (CEE) : un nouvel outil dans la recherche académique et industrielle, Revue des Maladies Respiratoires, 2018

Plantier L, Cazes A, Dinh-Xuan AT, Bancal C, Marchand-Adam S, Crestani B, Physiology of the lung in idiopathic pulmonary fibrosis, Eur Respir Rev. 2018

Bunge L, Baruch D, Plantier L, Mazars T, Roche N, Izadifar A; Médiflux, Study of the feasibility of spirometry in general practice, Revue des Maladies Respiratoires, 2018

Reminiac F, Vecellio L, Bodet-Contentin L, Gissot V, Le Pennec D, Salmon Gandonnière C, Cabrera M, Dequin PF, Plantier L, Ehrmann S, Nasal high-flow bronchodilator nebulization: a randomized cross-over study, Ann Intensive Care. 2018