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Announcement symposium “Epithelial cells: The conductors of inflammation” on March 15, 2025

Announcement symposium “Epithelial cells: the conductors of inflammation” 📅 Date: March 15, 2025; https://gremi.asso.fr/PGE2uk/uk_registration.htm Preliminary Program Printable Poster (A4, pdf) of the One-Day GREMI meeting Abstract deadline: January 20th, 2025 Conference site: Pasteur Institute (Paris) – Duclaux Lecture Theater (access: 205 rue de Vaugirard, Paris 15ème). At the entrance of the Pasteur Institute, your ID card will be requested.Registration payment includes lunch. Abstracts, posters (1m height x 0.70m large) and slides will be in English. Oral communications will preferably be in English or eventually in French. The poster size will be specified later. Suggested Hotel (Pasteur Institute rate, will be updated). The reservation of your room must be done directly with the hotel selected. Early reservation is recommended. Preferential rate granted to the Institut Pasteur according to the availabilities of the hotel. To take advantage of it, give the reference « Rate Institut Pasteur » when you book your room. The registration fees are 150 euros (full price) and 70 euros reduced price for the students, postdoc (<35 y/o) and ITA (technicians).For the students and technicians, in these cases a signed letter from their advisor verifying their status must be sent by email to xavier.norel@inserm.fr GREMI is a non-profit association exempted from commercial taxes, VAT non applicable

The CEPR is decked out in pink in support of #OctobreRose

« Pink October » celebrates its 31st anniversary in 2024. The event, symbolized by the pink ribbon, focuses on organized screening, in conjunction with the French National Cancer Institute. The slogan of the information and awareness campaign running throughout October is: « Stronger together! The aim of Pink October is to raise awareness and encourage breast cancer screening, with a view to reducing the number of deaths caused by this cancer.  

Discover the CEPR with the Science Festival 2024!

The CEPR was excited to take part in the Science Festival, inviting the public to discover the fascinating world of respiratory diseases. Through an open house event and a interactive stand at the Science Village, visitors of all ages had the chance to learn, explore, and engage with experts in a fun and interactive way! Précédent Suivant

A Grand Prize in France2030 iPhD national competition for CEPR!

CEPR Team 1’s SAChA project wins Grand Prize in France2030 iPhD national competition! Adeline Cezard, former PhD student and current young postdoctoral researcher with Team 1 CEPR, has won one of the Grand Prizes in the France2030 iPhD national competition! 🏆 This distinction highlights her contribution to the SAChA project, an innovative program dedicated to the development of antiviral therapies, co-funded by C-VaLo and the CATRIEM consortium.

4-year ANR funding obtained (PROJECT COORDINATION: M. Si-Tahar): Development of Succinate-based analogues and formulations against SARS-CoV-2 and influenza viruses-induced respiratory infections – (SuccesS)

The emergence of pandemic respiratory viruses is a major concern. Those viruses include coronaviruses such as SARS-CoV-2 and influenza A viruses (IAV). There are currently no efficient drugs against coronaviruses and the efficacy of anti-IAV drugs is disputed. Vaccination should constitute the most preventive strategy. However, the intrinsic antigenic drift of IAV impairs vaccine protection. Besides, previous coronaviruses crises showed that poorly neutralizing antibodies developed after vaccination may enhance subsequent infection. Current vaccine hesitancy also remains a barrier to full population inoculation against SARS-CoV-2. Our ANR project is thus aimed to develop an innovative metabolic therapy against those two viruses, delivered via the pulmonary route, based on (i) recent evidence that metabolites are key effectors of the host antimicrobial response and (ii) our preliminary data which identified two metabolites with anti-IAV and anti-SARS-CoV-2 antiviral activity. source : https://anr.fr/Projet-ANR-21-CE18-0061

Host succinate inhibits influenza virus infection through succinylation and nuclear retention of the viral nucleoprotein »

Antoine Guillon, Deborah Brea-Diakite, Adeline Cezard, Alan Wacquiez, Thomas Baranek, Jérôme Bourgeais, Frédéric Picou, Virginie Vasseur, Léa Meyer, Christophe Chevalier, Adrien Auvet, José M Carballido, Lydie Nadal Desbarats, Florent Dingli, Andrei Turtoi, Audrey Le Gouellec, Florence Fauvelle, Amélie Donchet, Thibaut Crépin, Pieter S Hiemstra, Christophe Paget, Damarys Loew, Olivier Herault, Mustapha Si-Tahar, […] source : https://febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.15229